A New Strategy for the Design of Drugs
ثبت نشده
چکیده
Protein crystallography enables us to elucidate the three—dimensional structures of small and large proteins with great accuracy, if suitable crystals can be prepared. Such three-dimensional structures fon a corner stone in a number of modern high-chem applications, such as design of new catalysts, vaccines, industrial enzymes, agro—chemicals and drugs. The way in which protein crystallography, computer graphics and molecular modelling helps, via a 'rational drug design" in the development of future drugs is outlined in this contributio'.
منابع مشابه
A New Framework for Advancement of Power Management Strategies in Hybrid Electric Vehicles
Power management strategies play a key role in the design process of hybrid electric vehicles. Electric Assist Control Strategy (EACS) is one of the popular power management strategies for hybrid electric vehicles (HEVs). The present investigation proposes a new framework to advance the EACS. Dynamic Programming method is applied to an HEV model in several drive cycles, and as a result, some op...
متن کاملA new switching strategy for exponential stabilization of uncertain discrete-time switched linear systems in guaranteed cost control problem
Uncertain switched linear systems are known as an important class of control systems. Performance of these systems is affected by uncertainties and its stabilization is a main concern of recent studies. Existing work on stabilization of these systems only provides asymptotical stabilization via designing switching strategy and state-feedback controller. In this paper, a new switching strate...
متن کاملThe Design of a New Double Loop Controller For Simultaneous Adjustment of Input and Output Voltages of Single-Phase Grid-Connected Inverter
Although LCL filters are used widely in the grid connected inverters to reduce high-orderharmonics, such a system increases system order and therefore sustainable design of closed-loopcontroller system will be complicated. Recently, the single-loop control strategy has beensuggested for L or LC filter based grid-connected inverters. However, the use of single-loopcontrol directly in LCL filter-...
متن کاملA Fast Strategy to Find Solution for Survivable Multicommodity Network
This paper proposes an immediately efficient method, based on Benders Decomposition (BD), for solving the survivable capacitated network design problem. This problem involves selecting a set of arcs for building a survivable network at a minimum cost and within a satisfied flow. The system is subject to failure and capacity restriction. To solve this problem, the BD was initially proposed with ...
متن کاملProfessional rational drug and biological product design methods based on chemoinformatics as a novel science
Background: The use of new technologies in the field of drug discovery and development plays an important role in introducing new and effective drugs, optimizing the properties of existing drugs and, in general the development of various drug-dependent industries, as well as the general health of human, animal and plant communities. These methods provide new drugs at...
متن کاملChaotic Genetic Algorithm based on Explicit Memory with a new Strategy for Updating and Retrieval of Memory in Dynamic Environments
Many of the problems considered in optimization and learning assume that solutions exist in a dynamic. Hence, algorithms are required that dynamically adapt with the problem’s conditions and search new conditions. Mostly, utilization of information from the past allows to quickly adapting changes after. This is the idea underlining the use of memory in this field, what involves key design issue...
متن کامل